NFL Week 5 Expert Betting Preview | Odds & Tips

NFL Week 5 Betting Preview Odds And Picks

After four weeks, there are six teams still undefeated and three winless in the NFL. Two of those winless teams are from New York.

The Titans and Steelers should be back in action after a forced bye week while the Lions and Packers will be on an actual bye week.

This is everything you need to know about the NFL week 5 games and betting odds.


Tampa Bay Buccaneers (3-1) at Chicago Bears (3-1)

Tampa Bay BuccaneersVs.Chicago Bears
-6 (-110)Spread+6 (-110)
O 44.5 (-110)TotalU 44.5 (-110)
Bet On Tampa Bay Buccaneers Vs. Chicago Bears NFL Week 5 Game at

Buccaneers vs. Bears Game Details

  • Date: Thursday, October 8, 2020 | 8:20 PM ET
  • Venue: Soldier Field, Chicago, IL
  • TV: FOX / NFL Network

Buccaneers vs. Bears Breakdown

Tom Brady became the oldest QB to throw 5 TD passes in a game. But he has also thrown four PickSixes in the last six games, which is insane. He still doesn’t look entirely comfortable in this offense. I know how weird that sounds after he tossed 5 TDs on Sunday.

The Bucs lost TE OJ Howard (Achilles) for the rest of the season. WR Chris Godwin won’t play on Thursday either, and Mike Evans is hobbling an ankle injury.

Talking about bad offense, the Bears have the ninth-worst in the league. They ran the ball for 28 yards against the Colts during their first loss of the season. Chicago also had 103 yards on penalties.

Public: 61% is with the Bucs -6.

Buffalo Bills (4-0) at Tennessee Titans (3-0)

There are currently no odds for this game. Be sure to go to to check on the latest odds for all other NFL games that will be played in Week 5.

Bills vs. Titans Game Details

  • Date: Sunday, October 11, 2020 | 1:00 PM ET
  • Venue: Nissan Stadium, Nashville, TN
  • TV: CBS

Bills vs. Titans Breakdown

The Bills vs. Titans game is off the board for obvious reasons. ESPN reported that Tennessee had zero positive COVID tests on Monday and Tuesday, but the NFL hasn’t said an official word about the status of the game. Update: The game is unlikely to be played as another positive test has appeared for the Titans.

Carolina Panthers (2-2) at Atlanta Falcons (0-4)

Carolina PanthersVs.Atlanta Falcons
+3.5 (-110)Spread-3.5 (-110)
Bet On Carolina Panthers Vs. Atlanta Falcons NFL Week 5 Game at

Panthers vs. Falcons Game Details

  • Date: Sunday, October 11, 2020 | 1:00 PM ET
  • Venue: Mercedes-Benz Stadium, Atlanta, GA
  • TV: FOX

Panthers vs. Falcons Breakdown

The Panthers are sneaky fun. Carolina has the 8th best passing offense in the league and has won two in a row.

The Falcons lost free safety Damontae Kazee for the rest of the season with an Achilles tendon injury. WR Julio Jones also left the game against the Packers with a hamstring injury.

Public: 91% is with the Panthers +3.5.

Las Vegas Raiders (2-2) at Kansas City Chiefs (4-0)

Las Vegas RaidersVs.Kansas City Chiefs
+12.5 (-110)Spread-12.5 (-110)
O 56 (-110)TotalU 56 (-110)
Bet On Las Vegas Raiders Vs. Kansas City Chiefs NFL Week 5 Game at

Raiders vs. Chiefs Game Details

  • Date: Sunday, October 11, 2020 | 1:00 PM ET
  • Venue: Arrowhead Stadium, Kansas City, MO
  • TV: CBS

Raiders vs. Chiefs Breakdown

The Raiders started 2-0, and they are likely to be 2-3 after visiting the Chiefs this Sunday. RB Josh Jacobs scored three TDs in the opening weekend against Carolina. He hasn’t scored since, nor he has broken the 100-rushing yards mark in a game this season.

Patrick Mahomes is 4-0 against the Raiders in his career. He has thrown 11 TDs and just one interception in those games.

Public: 67% is with the Chiefs -12.5.

Arizona Cardinals (2-2) at NY Jets (0-4)

Arizona CardinalsVs.NY Jets
-6.5 (-110)Spread+6.5 (-110)
O 47.5 (-110)TotalU 47.5 (-110)
Bet On Arizona Cardinals Vs. NY Jets NFL Week 5 Game at

Cardinals vs. Jets Game Details

  • Date: Sunday, October 11, 2020 | 1:00 PM ET
  • Venue: MetLife Stadium, East Rutherford, NJ
  • TV: FOX

Cardinals vs. Jets Breakdown

Did we overestimate the Cardinals? Their passing offense is 24th in the league, and their defense allowed 444 from the Panthers on Sunday. All those yards without Christian McCaffrey.

Nevertheless, they should bounce back this weekend.

How does Adam Gase still have a job?

Public: 89% is with the Cards -6.5.

Philadelphia Eagles (1-2-1) at Pittsburgh Steelers (3-0)

Philadelphia EaglesVs.Pittsburgh Steelers
+7 (-110)Spread-7 (-110)
O 46 (-110)TotalU 46 (-110)
Bet On Philadelphia Eagles Vs. Pittsburgh Steelers NFL Week 5 Game at

Eagles vs. Steelers Game Details

  • Date: Sunday, October 11, 2020 | 1:00 PM ET
  • Venue: Heinz Field, Pittsburgh, PA
  • TV: FOX

Eagles vs. Steelers Breakdown

It was a great win by the Eagles on Sunday, but you can see all the flaws this team has.

Carson Wentz was running for his life against a depleted San Francisco defense. Now he gets the rested-Steelers defense. That’s a recipe for a Philadelphia disaster.

LA Rams (3-1) at Washington Football Team (1-3)

LA RamsVs.Washington Football Team
-9 (-110)Spread+9 (-110)
O 46 (-110)TotalU 46 (-110)
Bet On LA Rams Vs. Washington Football Team NFL Week 5 Game at

Rams vs. Football Team Game Details

  • Date: Sunday, October 11, 2020 | 1:00 PM ET
  • Venue: FedExField, Landover, MD
  • TV: FOX

Rams vs. Football Team Breakdown

The Rams struggled on offense last week against the Giants. They will get another lousy team this week when they visit Washington.

LA will face San Francisco in Week 6. They better not underestimate the Football Team as they did against the Giants.

Cincinnati Bengals (1-2-1) at Baltimore Ravens (3-1)

Cincinnati BengalsVs.Baltimore Ravens
+13.5 (-110)Spread-13.5 (-110)
O 52 (-110)TotalU 52 (-110)
Bet On Cincinnati Bengals Vs. Baltimore Ravens NFL Week 5 Game at

Bengals vs. Ravens Game Details

  • Date: Sunday, October 11, 2020 | 1:00 PM ET
  • Venue: M&T Bank Stadium, Baltimore, MD
  • TV: CBS

Bengals vs. Ravens Breakdown

Joe Burrow had his first career win against the Jaguars last week. Facing Baltimore won’t be as sweet.

Burrow was sacked only once against Jacksonville. I don’t think he will have the same luck this week.

This is the second week in a row the Ravens are favorites by over 13 points. They covered without a problem against Washington last week.

Public: 93% is with the Ravens -13.5.

Jacksonville Jaguars (1-3) at Houston Texans (0-4)

Jacksonville JaguarsVs.Houston Texans
+6.5 (-110)Spread-6.5 (-110)
O 54 (-110)TotalU 54 (-110)
Bet On Jacksonville Jaguars Vs. Houston Texans NFL Week 5 Game at

Jaguars vs. Texans Game Details

  • Date: Sunday, October 11, 2020 | 1:00 PM ET
  • Venue: NRG Stadium, Houston, TX
  • TV: CBS

Jaguars vs. Texans Breakdown

The Jaguars have lost three in a row since surprising the Colts. How weird does that Week 1 result look now?

QB Gardner Minshew has thrown four interceptions in the last three games.

The Texans are winless after four tries. I feel like Bill O’Brien kidnapped QB Deshaun Watson for years. Now, he’s finally free.

Miami Dolphins (1-3) at San Francisco 49ers (2-2)

Miami DolphinsVs.San Francisco 49ers
+8.5 (-110)Spread-8.5 (-110)
Bet On Miami Dolphins Vs. San Francisco 49ers NFL Week 5 Game at

Dolphins vs. 49ers Game Details

  • Date: Sunday, October 11, 2020 | 4:05 PM ET
  • Venue: Levi’s Stadium, Santa Clara, CA
  • TV: FOX

Dolphins vs. 49ers Breakdown

Miami battled against Seattle last week, but in the end, the Seahawks were better. There is no shame in losing to a better team.

San Francisco can’t say the same. They truly disappointed by losing to a depleted Eagles team that couldn’t protect their QB all night.

The Niners will evaluate the QB situation. Jimmy Garoppolo could be back, but if not, HC Kyle Shanahan will have to decide between Nick Mullens and CJ Beathard. Yikes.

Indianapolis Colts (3-1) at Cleveland Browns (3-1)

Indianapolis ColtsVs.Cleveland Browns
-2.5 (-110)Spread+2.5 (-110)
O 47.5 (-110)TotalU 47.5 (-110)
Bet On Indianapolis Colts Vs. Cleveland Browns NFL Week 5 Game at

Colts vs. Browns Game Details

  • Date: Sunday, October 11, 2020 | 4:25 PM ET
  • Venue: FirstEnergy Stadium, Cleveland, OH
  • TV: CBS

Colts vs. Browns Breakdown

Indianapolis has won three straight games, and they have the best defense in the NFL in years and points allowed.

We made fun of the Browns after losing in Baltimore in Week 1, but now they have won three in a row. Cleveland has scored 39.3 points in those three wins.

The Browns won’t have RB Nick Chubb for several weeks after he suffered an MLC injury. Kareem Hunt should be good enough to replace him. Hunt is averaging 5.5 yards per carry.

Public: 54% is with the Browns +2.5.

NY Giants (0-4) at Dallas Cowboys (1-3)

NY GiantsVs.Dallas Cowboys
+9 (-110)Spread-9 (-110)
O 54 (-110)TotalU 54 (-110)
Bet On NY Giants Vs. Dallas Cowboys NFL Week 5 Game at

Giants vs. Cowboys Game Details

  • Date: Sunday, October 11, 2020 | 4:25 PM ET
  • Venue: AT&T Stadium, Arlington, TX
  • TV: CBS

Giants vs. Cowboys Breakdown

I just threw up in my mouth.

The Cowboys are 9-point favorites, but that spread seems high considering Dallas has allowed a league’s worst 36.5 points per game this season.

Public: 63% is with the Cowboys -9.

Denver Broncos (1-3) at New England Patriots (2-2)

New England is a -10.5 point favorite over the visiting Broncos. Both teams have suffered from a litany of injuries and COVID-related inactive. The Patriots are coming off a short week after losing at Kansas City. The Broncos are coming into this game after a win last Thursday against the lowly Jets.

Broncos vs. Patriots Game Details

  • Date: Sunday, October 11, 2020 | 4:25 PM ET
  • Venue: Gillette Stadium, Foxboro, MA
  • TV: CBS

Broncos vs. Patriots Breakdown

Remember when Peyton Manning and Tom Brady made this matchup into a fantastic rivalry.

Now we get Brett Rypien against Brian Hoyer or Jarett Stidham.

Minnesota Vikings (1-3) at Seattle Seahawks (4-0)

Minnesota VikingsVs.Seattle Seahawks
+7 (-110)Spread-7 (-110)
O 57.5 (-110)TotalU 57.5 (-110)
Bet On Minnesota Vikings Vs. Seattle Seahawks NFL Week 5 Game at

Vikings vs. Seahawks Game Details

  • Date: Sunday, October 11, 2020 | 8:20 PM ET
  • Venue: CenturyLink Field, Seattle, WA
  • TV: NBC

Vikings vs. Seahawks Breakdown

The Vikings finally won this season. Their formula was get the ball to Dalvin Cook and get out of the way. Thirty-nine of its 65 offensive plays (60%) were design runs.

The problem is Seattle has the third-best rushing defense in the NFL.

Public: 60% is with the Seahawks -7.

LA Chargers (1-3) at New Orleans Saints (2-2)

LA ChargersVs.New Orleans Saints
+7.5 (-110)Spread-7.5 (-110)
O 52 (-110)TotalU 52 (-110)
Bet On LA Chargers Vs. New Orleans Saints NFL Week 5 Game at

Chargers vs. Saints Game Details

  • Date: Monday, October 12, 2020 | 8:15 PM ET
  • Venue: Mercedes-Benz Superdome, New Orleans, LA
  • TV: ESPN

Chargers vs. Saints Breakdown

The Chargers can’t go back to Tyrod Taylor, right?

Rookie QB Justin Herbert threw 290 yards and three scores against Tampa Bay. He only didn’t connect with five of his attempts. Monday Night will be his first Primetime game.

The team lost RB Austin Ekeler several weeks with a severe hamstring injury.

New Orleans has averaged 29.6 points per game in three games where they didn’t have WR Michael Thomas. The Saints have the 5th best scoring offense in the NFL, despite most people keep saying QB Drew Brees is washed.

Public: 75% is with the Chargers +7.5.

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About the Author

Alonzo Solano

Alonzo Solano

Sports Analyst and Content Writer

Alonzo is a Sports Betting Analyst and casino games enthusiast who has covered Football extensively at SBS, but don’t be surprised if you read him on other sports. He's the host of the NFL Latino TV podcast.

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