NFL Week 6 Expert Betting Preview | Odds & Tips

NFL Week 6 Expert Betting Preview

Top NFL Games To Bet On During Week 6

The San Francisco 49ers and New England Patriots are now the only two unbeaten teams remaining in the NFL after five weeks of action.

NFL Week 6 will have four franchises on their bye weeks: Bills, Bears, Colts, & Raiders. For the second weekend in a row, London will host an NFL game at Tottenham Hotspur stadium.

Let’s break down the big news for this football weekend, along with the NFL Week 6 betting odds and analysis:

NY Giants (2-3) Vs. New England Patriots (5-0)

Giants vs. Patriots
+675 Moneyline -1050
+17 (-110) Spread -17 (-110)
O 42 (-110) Total U 42 (-110)
Bet On Giants vs. Patriots NFL Week 6 Game At MyBookie.ag

The betting line for this game opened with the Patriots -17.5. It has moved half a point down, but it might be even higher by kickoff time with the Giants suffering from many different injuries.

The Giants ruled out WR Sterling Shepard and RB Saquon Barkley due to injuries. New York could be without TE Evan Engram for Thursday as well, as he deals with a sprained MCL.

New England owns the best scoring defense in the league, giving up 6.8 points per game after five games. They will face a rookie QB on a short week without many of his weapons.

Also, what would be the over/under shots we see David Tyree catch on TV before and during the game? I have it at 3.5!

Giants vs. Patriots Game Information

  • Date: Thursday, October 10, 2019
  • Game Time: 8:20 PM ET
  • Venue: Gillette Stadium, Foxboro, MA
  • TV: FOX / NFL Network

Carolina Panthers (3-2) Vs. Tampa Bay Buccaneers (2-3)

Panthers vs. Buccaneers
-130 Moneyline +105
-2 (-110) Spread +2 (-110)
O 48 (-110) Total U 48 (-110)
Bet On Panthers vs. Buccaneers NFL Week 6 Game At MyBookie.ag

Just weeks ago, the Panthers and the Bucs gave us one of the worst Thursday Night games I can remember. For some reason, the NFL decided it was necessary to feature this game early on Sunday.

The Panthers are now -2 after the game opened as a pick’em. The overwhelming praise on RB Christian McCaffrey’s season is everywhere. The guy is a stud who can do it all.

Can McCaffrey be a legit MVP candidate at the end of the season? He will have to run for 2000 yards and take the Panthers to the playoffs. I can see the first part happening, but I’m not sure about the second.

Tampa Bay travels to London without two starters on their offensive line. Right tackle Demar Dotson won’t play due to hamstring and calf injuries. Right guard Alex Cappa broke his left arm against the Saints last week.

Panthers vs. Buccaneers Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 9:30 AM ET
  • Venue: Tottenham Hotspur Stadium, London
  • TV: NFL Network

Seattle Seahawks (4-1) Vs. Cleveland Browns (2-3)

Seahawks vs. Browns
-125 Moneyline +105
-1.5 (-110) Spread +1.5 (-110)
O 47.5 (-110) Total U 47.5 (-110)
Bet On Seahawks vs. Browns NFL Week 6 Game At MyBookie.ag

Seattle has a ten-day rest to prepare for this game, while Cleveland will be on a short week.

Brown’s QB Baker Mayfield leads the league with eight interceptions, and he’s one of the most sacked QBs in the NFL with 16.

The good news for Cleveland is that only six teams have recorded fewer sacks this season than Seattle’s ten. The Seahawks never got to Jared Goff last week.

Seahawks vs. Browns Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 1:00 PM ET
  • Venue: FirstEnergy Stadium, Cleveland, OH
  • TV: FOX

Houston Texans (3-2) Vs. Kansas City Chiefs (4-1)

Texans vs. Chiefs
+190 Moneyline -230
+4.5 (-110) Spread -4.5 (-110)
O 55 (-110) Total U 55 (-110)
Bet On Texans vs. Chiefs NFL Week 6 Game At MyBookie.ag

Patrick Mahomes and Deshaun Watson have combined for 22 touchdowns and one interception this year. The game total won’t be high enough for these two ballers.

Mahomes, however, has thrown just one touchdown in the last two outings. Watson is coming off a 400+ yards performance with 5 TDs and a perfect passer rating of 158.3. He had as many TDs as incomplete passes against Atlanta.

Kansas City is -4.5 for this game after it opened -5. Mahomes tweaked his ankle against the Colts last week, but he should be good to go. I can’t say the same about DL Chris Jones (groin injury), linebacker Anthony Hitchens (groin) and DT Xavier Williams (ankle).

The Chiefs might have back WR Tyreek Hill for this game. Hill hasn’t played since he suffered a shoulder injury in week one.

Texans vs. Chiefs Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 1:00 PM ET
  • Venue: Arrowhead Stadium, Kansas City, MO
  • TV: CBS

Washington Redskins (0-5) Vs. Miami Dolphins (0-4)

Redskins vs. Dolphins
-190 Moneyline +160
-3.5 (-110) Spread +3.5 (-110)
O 41 (-110) Total U 41 (-110)
Bet On Redskins vs. Dolphins NFL Week 6 Game At MyBookie.ag

The Garbage Bowl will have the Redskins and Dolphins looking to add their first win of the season. But are we sure they want to win?

Miami is definitely in taking mode while Washington wouldn’t mind having the first pick in the NFL Draft either.

The Redskins just fired Jay Gruden on Sunday night in a move that shocked no one.

Washington has the third-worst defense in the league, allowing 30.2 points per game. It just so happens that Miami is far more dismal on this front, giving up 40.8 PPG.

Redskins vs. Dolphins Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 1:00 PM ET
  • Venue: Hard Rock Stadium, Miami Gardens, FL
  • TV: CBS

Philadelphia Eagles (3-2) Vs. Minnesota Vikings (3-2)

Eagles vs. Vikings
+120 Moneyline -145
+3 (-110) Spread -3 (-110)
O 43.5 (-110) Total U 43.5 (-110)
Bet On Eagles vs. Vikings NFL Week 6 Game At MyBookie.ag

The Vikings opened -3 at home against Philadelphia. The line hasn’t moved at all, although 67% of the betting public is taking the Eagles. This number might not be there by kickoff time.

Adam Thielen called out QB Kirk Cousins last week, and it worked. Cousins threw 303 yards against the Giants. The wide receiver also awoke from his early-season slumber, notching 130 yards and two touchdowns.

The issue is Philadelphia is coming off a game where they recorded ten sacks against the Jets. Protecting QB Kirk Cousins in the pocket has been the main concern for the Vikings over the past two seasons.

Eagles vs. Vikings Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 1:00 PM ET
  • Venue: U.S. Bank Stadium, Minneapolis, MN
  • TV: FOX

New Orleans Saints (4-1) Vs. Jacksonville Jaguars (2-3)

Saints vs. Jaguars
+120 Moneyline -125
PK (-110) Spread PK (-110)
O 44.5 (-110) Total U 44.5 (-110)
Bet On Saints vs. Jaguars NFL Week 6 Game At MyBookie.ag

This game opened as a pick’em. Several sportsbooks have the Saints -1 and others even -1.5. MyBookie.ag maintains this game as pick’em, so if you like New Orleans on the road, you should jump on it right now.

Since Drew Brees went down, the Saints are 3-0. Their defense held both the Cowboys and Buccaneers offenses to fewer than 270 total yards in that stretch.

The Jaguars defense allowed 237 purpose yards and three scores from Christian McCaffrey last week. It doesn’t get easier this week when facing RB Alvin Kamara.

Saints vs. Jaguars Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 1:00 PM ET
  • Venue: TIAA Bank Field, Jacksonville, FL
  • TV: CBS

Cincinnati Bengals (0-5) Vs. Baltimore Ravens (3-2)

Bengals vs. Ravens
+410 Moneyline -570
+12 (-120) Spread -12 (+100)
O 48 (-110) Total U 48 (-110)
Bet On Bengals vs. Ravens NFL Week 6 Game At MyBookie.ag

The AFC North doesn’t look to be in great shape.

This is the 7th time the Bengals started 0-5 since 1990 and first since 2008. It is the most in the NFL in that timespan.

The Ravens have the second-best rushing offense in the NFL, averaging 192.2 yards per game. Their most insane stat is they lead the league in points scored averaging 32.2 PPG. It’s very un-Ravenlike. However, their schedule has been rather easy to start the year, so that’s something to keep in mind when looking at their offense as it stands now.

Bengals vs. Ravens Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 1:00 PM ET
  • Venue: M&T Bank Stadium, Baltimore, MD
  • TV: CBS

San Francisco 49ers (4-0) Vs. Los Angeles Rams (3-2)

49ers vs. Rams
+175 Moneyline -210
+3.5 (-105) Spread -3.5 (-115)
O 50.5 (-110) Total U 50.5 (-110)
Bet On 49ers vs. Rams NFL Week 6 Game At MyBookie.ag

The 49ers are the only unbeaten team in the NFC, but the Rams are not ready to give up the favorite label in the division. Plus, Los Angeles has ten days to prepare for this game.

San Francisco leads the NFL averaging 200.0 rushing yards per game. On Monday night, they destroyed the Browns by recording 275 rushing yards in 31-3 blowout victory.

The Rams are -3.5 for this game after opening -4. Can you imagine seeing this betting line in August? You would have almost certainly thought the Rams would be -7 or more.

Los Angeles has never lost three games in a row since Sean McVay took over as the head coach in 2017.

49ers vs. Rams Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 4:05 PM ET
  • Venue: Los Angeles Memorial Coliseum, Los Angeles, CA
  • TV: FOX

Atlanta Falcons (1-4) Vs. Arizona Cardinals (1-3-1)

Falcons vs. Cardinals
-145 Moneyline +125
-2.5 (-120) Spread +2.5 (+100)
O 52 (-110) Total U 52 (-110)
Bet On Falcons vs. Cardinals NFL Week 6 Game At MyBookie.ag

The Falcons have not won on the road this season. The Cardinals got their first victory of the year last week after defeating the visiting Bengals. Atlanta is -2.5 at MyBookie.ag after opening -1.

Atlanta is coming off a 53-32 loss to Houston. The last time the Falcons allowed that many points in a game was in 2004 during a 56-10 defeat to Kansas City.

Also, the 53 points allowed are the third most by any franchise this season. Miami gave up 59 to Baltimore, and the Rams allowed 55 against Tampa Bay. The Falcons being a road favorite is hard to swallow, but they do have a talented roster, at least on the offensive side of the ball.

Falcons vs. Cardinals Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 4:05 PM ET
  • Venue: State Farm Stadium, Glendale, AZ
  • TV: FOX

Tennessee Titans (2-3) Vs. Denver Broncos (1-4)

Titans vs. Broncos
+120 Moneyline -140
+2.5 (-110) Spread -2.5 (-110)
O 39 (-110) Total U 39 (-110)
Bet On Titans vs. Broncos NFL Week 6 Game At MyBookie.ag

The Broncos opened -1 but now are now -2.5 after getting their first win of the season against the Chargers last week.

The crazy thing about Denver is they have had the led twice with less than a minute to play and lost both times. With a little luck, the Broncos could have been 3-2.

The Titans decided to cut Cairo Santos after he cost the team 12 points after missing four field goals in the 14-7 loss to the Buffalo Bills. Tennessee’s new kicker is Cody Parkey, who Bears’ fans remember well.

Titans vs. Broncos Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 4:25 PM ET
  • Venue: Empower Field at Mile High, Denver, CO
  • TV: FOX

Dallas Cowboys (3-2) Vs. NY Jets (0-4)

Cowboys vs. Jets
N/A Moneyline N/A
-8.5 (-110) Spread +8.5 (-110)
N/A Total N/A
Bet On Cowboys vs. Jets NFL Week 6 Game At MyBookie.ag

The Dallas Cowboys are 3-0 against losing teams and 0-2 against winning squads. In theory, this meeting against the Jets is right up Dallas’ alley.

Dak Prescott recorded zero yards on third-down plays last week against the Packers. He has been heavily criticized in the media after Sunday’s loss against Green Bay.

The Jets activated QB Sam Darnold after weeks dealing with mono. New York has the second-worst offense in the NFL, averaging 9.8 points per game. The team has more defensive and special teams’ TDs (3) than offensive (2).

Cowboys vs. Jets Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 4:25 PM ET
  • Venue: MetLife Stadium, East Rutherford, NJ
  • TV: CBS

Pittsburgh Steelers (1-4) Vs. Los Angeles Chargers (2-3)

Steelers vs. Chargers
N/A Moneyline N/A
+7 (-110) Spread -7 (-110)
N/A Total N/A
Bet On Steelers vs. Chargers NFL Week 6 Game At MyBookie.ag

The Steelers are set to be on their third-string QB after Mason Rudolph’s scary hit against the Baltimore Ravens.

Undrafted rookie Devlin Hodges will be under center this week. Hodges played for Samford and is the all-time school leader with 14,584 yards, 111 TDs, and 41 interceptions.

The Chargers have lost three of their last four games. Their only win in that span was against the lousy Miami Dolphins.

Los Angeles is a touchdown favorite in most markets, but if you want to shop around, you can find the Chargers -6.5 at some sportsbooks.

Steelers vs. Chargers Game Information

  • Date: Sunday, October 13, 2019
  • Game Time: 8:20 PM ET
  • Venue: Dignity Health Sports Park, Carson, CA
  • TV: NBC

Detroit Lions (2-1-1) Vs. Green Bay Packers (4-1)

Lions vs. Packers
+185 Moneyline -220
+4.5 (-110) Spread -4.5 (-110)
O 47 (-110) Total U 47 (-110)
Bet On Lions vs. Packers NFL Week 6 Game At MyBookie.ag

The Packers opened -6 but currently, are -4.5 at MyBookie.ag. 54% of the betting public is taking Detroit with the points.

The Lions are coming off a bye week. Detroit has been a surprising team this season, but if they want to be taken seriously, they need to beat their divisional opponents, starting with the Packers.

Aaron Rodgers didn’t throw a touchdown pass last week against Dallas, but RB Aaron Jones became the first Packer to run for four scores since 2000.

Lions vs. Packers Game Information

  • Date: Monday, October 14, 2019
  • Game Time: 8:15 PM ET
  • Venue: Lambeau Field, Green Bay, WI
  • TV: ESPN

Bet On NFL Week 6 Games At MyBookie Sportsbook

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Alonzo Solano

Alonzo Solano - Sports Analyst & Picks Writer

Alonzo is a Sports Analyst who has covered College Football and NFL odds for SafestBettingSites but don’t be surprised if you read him on any other sport. He’s a gaming analyst looking for winners every weekend.

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