NFL Week 10 Expert Betting Preview | Odds & Tips

NFL Week 10 Expert Betting Preview And Odds Analysis

Top NFL Games To Bet On During Week 10

Even though six teams will be on a bye week, the NFL Week 10 could be one of the best of the season.

Broncos, Patriots, Eagles, Redskins, Jaguars, and Texans will be resting, but the lineup of games brings three games between teams with a winning record, two of them during primetime.

After the Patriots lost in Baltimore, the 49ers are the only unbeaten team remaining. Let’s dive into the NFL Week 10.

Los Angeles Chargers (4-5) At Oakland Raiders (4-4)

Chargers vs. Raiders
-118 Moneyline -102
-1 (-110) Spread +1 (-110)
O 48.5 (-110) Total U 48.5 (-110)
Bet On Chargers vs. Raiders NFL Week 10 Game At

Quietly the Chargers have won two in a row and are back in the wildcard race. The change at the offensive coordinator position sure helped the team as they outgained the Packers 442-184 in total yards last week.

The Raiders only play high scoring games this season. Oakland allows 27.0 points per game and has the worst passing defense in the entire NFL.

Over the last six games, any game the Raiders have played averages 53.4 points in total points between Oakland and whoever is their opponent.

Chargers Vs. Raiders Game Information

  • Date: Thursday, November 7, 2019
  • Game Time: 8:20 PM ET
  • Venue: RingCentral Coliseum, Oakland, CA
  • TV: FOX / NFL Network

Detroit Lions (3-4-1) At Chicago Bears (3-5)

Lions vs. Bears
+125 Moneyline -145
+2.5 (-110) Spread -2.5 (-110)
 O 42.5 (-110) Total  U 42.5 (-110)
Bet On Lions vs. Bears NFL Week 10 Game At

Both the Lions and Bears are right on the edge of missing their last chance to turn around the season. Whoever loses this game will probably say goodbye to the playoffs’ train.

The Chicago Bears opened -3, but in a few markets, the betting line has dropped to -2.5. So far, 62% of the betting public is gladly taking the Lions with the points.

Chicago has the third-worst passing offense in the NFL, only above the Washington Redskins and NY Jets.

Lions Vs. Bears Game Information

  • Date: Sunday, November 10, 2019
  • Game Time: 1:00 PM ET
  • Venue: Soldier Field, Chicago, IL
  • TV: CBS

Baltimore Ravens (6-2) At Cincinnati Bengals (0-8)

Ravens vs. Bengals
-460 Moneyline +365
-10.5 (-110) Spread +10.5 (-110)
O 45.5 (-110) Total U 45.5 (-110)
Bet On Ravens vs. Bengals NFL Week 10 Game At

The Ravens are coming off their best win in the Lamar Jackson era. Their next challenge should be a lot easier, as they facing the only team without a win in the NFL so far this season.

Baltimore not only has the best rushing offense in the NFL, averaging 204.9 rushing yards per game but the best scoring unit as well, scoring 31.4 points per game.

The Bengals will go with rookie QB Ryan Finley under center for this game instead of Andy Dalton. Finley was selected in the fourth round of the 2019 NFL draft from North Carolina State.

Ravens Vs. Bengals Game Information

  • Date: Sunday, November 10, 2019
  • Game Time: 1:00 PM ET
  • Venue: Paul Brown Stadium, Cincinnati, OH
  • TV: CBS

Buffalo Bills (5-2) At Cleveland Browns (2-6)

Bills vs. Browns
+115 Moneyline -145
+2.5 (-110) Spread -2.5 (-110)
O 40 (-110) Total U 40 (-110)
Bet On Bills vs. Browns NFL Week 10 Game At

The Buffalo Bills haven’t lost on the road this season, and the Browns haven’t won at home. This could be the last nail in Cleveland’s coffin.

The Browns are a mess dropping the last four games in a row. They just released safety Jermaine Whitehead because he spent his Sunday night fighting with fans on Twitter.

Cleveland’s offense is averaging 15.7 points per game in the last four losses. QB Baker Mayfield hasn’t thrown more than one TD in a game during the entire season.

Somehow the Browns opened -3, but the line has dropped to -2.5 in many sports betting sites. 72% of the betting public is siding with the Bills and the points.

Bills Vs. Browns Game Information

  • Date: Sunday, November 10, 2019
  • Game Time: 1:00 PM ET
  • Venue: FirstEnergy Stadium, Cleveland, OH
  • TV: CBS

Kansas City Chiefs (6-3) At Tennessee Titans (4-5)

Chiefs vs. Titans
N/A Moneyline N/A
-3.5 (-110) Spread +3.5 (-110)
N/A Total N/A
Bet On Chiefs vs. Titans NFL Week 10 Game At

There hasn’t been an official announcement, but all the rumors suggest this is the game where Patrick Mahomes will be back under center.

Kansas City Chiefs opened -3.5 on the road, and some betting markets even have them -4. However, the betting line is off in many places as we wait for the confirmation that Mahomes will play.

Even if Mahomes is not ready, the team should be excellent under veteran Matt Moore since he took over, Moore as thrown four touchdowns without an interception while posting a 2-1 record beating the Broncos and Vikings while barely losing to the Packers.

Chiefs Vs. Titans Game Information

  • Date: Sunday, November 10, 2019
  • Game Time: 1:00 PM ET
  • Venue: Nissan Stadium, Nashville, TN
  • TV: CBS

Atlanta Falcons (1-7) At New Orleans Saints (7-1)

Falcons vs. Saints
+475 Moneyline -650
+13 (-110) Spread -13 (-110)
O 51 (-110) Total U 51 (-110)
Bet On Falcons vs. Saints NFL Week 10 Game At

For years the Falcons vs. Saints was the marquee game in the NFC South but not this year. Atlanta has lost six games in a row and will go to New Orleans with veteran Matt Schaub under center.

New Orleans has won six in a row, and Drew Brees had two weeks to get even healthier after coming back against Arizona in week eight.

The Saints opened -14 at home, and 61% of the public is laying down the points and taking New Orleans to cover the spread. The betting line has been adjusted in many sports betting sites, and it can be found at -13, and in some places even at -12.5.

Falcons Vs. Saints Game Information

  • Date: Sunday, November 10, 2019
  • Game Time: 1:00 PM ET
  • Venue: Mercedes-Benz Superdome, New Orleans, LA
  • TV: FOX

NY Giants (2-7) At NY Jets (1-7)

Giants vs. Jets
N/A Moneyline N/A
-2.5 (-110) Spread +2.5 (-110)
N/A Total N/A
Bet On Giants vs. Jets NFL Week 10 Game At

The battle to see who is the worst team in New York will be in full motion on Sunday. The Giants have dropped five in a row while the Jets three straight, including an embarrassing loss to the Miami Dolphins.

Jets RB Le’Veon Bell had an MRI for a potential knee injury, but the team hasn’t mentioned if the running back will be available for Sunday. Jets quarterback Sam Darnold has nine interceptions this season, one more than the Giants’ rookie Daniel Jones.

Let’s not forget Darnold missed three games this year due to mononucleosis. Jones, however, leads the league with 16 turnovers, including fumbles. The Giants opened -2.5 for this game, but now the line has dropped to -2 and in many cases, to -1.5.

Giants Vs. Jets Game Information

  • Date: Sunday, November 10, 2019
  • Game Time: 1:00 PM ET
  • Venue: MetLife Stadium, East Rutherford, NJ
  • TV: FOX

Arizona Cardinals (3-5-1) At Tampa Bay Buccaneers (2-6)

Cardinals vs. Buccaneers
+185 Moneyline -225
+4.5 (-110) Spread -4.5 (-110)
O 52 (-110) Total U 52 (-110)
Bet On Cardinals vs. Buccaneers NFL Week 10 Game At

The Cardinals arrive at this game with ten days to prepare after losing to the Niners in the NFL Week 9 Thursday Night Football matchup.

Tailback Kenyan Drake had 110 yards and a touchdown on his first game with the Arizona Cardinals even though he spent only two days with the team before his debut.

Tampa Bay has the fourth-best scoring offense in the NFL, averaging 28.8 points per game. The Buccaneers are the only team with a losing record out of the 11 most scoring squads in the NFL.

Their defense allows the second-most points in league with 31.5 points per game. Only the Miami Dolphins give up more.

Cardinals Vs. Buccaneers Game Information

  • Date: Sunday, November 10, 2019
  • Game Time: 1:00 PM ET
  • Venue: Raymond James Stadium, Tampa, FL
  • TV: FOX

Miami Dolphins (1-7) At Indianapolis Colts (5-3)

Dolphins vs. Colts
+400 Moneyline -500
+10.5 (-110) Spread -10.5 (-110)
O 43.5 (-110) Total U 43.5 (-110)
Bet On Dolphins vs. Colts NFL Week 10 Game At

Fresh off their first win of the season, Miami will try to put together a winning streak by visiting the Colts. Indianapolis will be without QB Jacoby Brissett, who suffered an MCL sprain in the loss against the Steelers on Sunday.

Brian Hoyer, who recorded three touchdowns and one interception against Pittsburgh, will oversee the offense. The Colts opened -12, but now the line is -10.5 in most sports betting sites. 64% of the public is riding the Dolphins with the points.

Dolphins vs. Colts Game Information

  • Date: Sunday, November 10, 2019
  • Game Time: 4:05 PM ET
  • Venue: Lucas Oil Stadium, Indianapolis, IN
  • TV: CBS

Carolina Panthers (5-3) At Green Bay Packers (7-2)

Panthers vs. Packers
+185 Moneyline -225
+5 (-110) Spread -5 (-110)
O 42.5 (-110) Total U 42.5 (-110)
Bet On Panthers vs. Packers NFL Week 10 Game At

The Packers’ loss in Los Angeles was a wake-up call for the team. The Green Bay Packers had 50 total yards by the third quarter and was completely dominated by the Chargers.

Aaron Rodgers’s chances to win the MVP took a massive hit on Sunday. He completed 23 of 35 passes for 161 yards and one score. Most of his yards and the touchdown pass came in garbage time.

Carolina has won five of his six games with Kyle Allen under center. RB Christian McCaffrey might be in for -another- massive game against the Packers defense.

McCaffrey leads the league with a 110.1 rushing yards per game. Green Bay has one of the worst defenses against the run, allowing 127.1 rushing yards per game.

The Packers opened -6 at home, but the line now is -5.5 in most markets. There are a few with the odds at -5 and even a couple with Green Bay -4.5.

Panthers Vs. Packers Game Information

  • Date: Sunday, November 10, 2019
  • Game Time: 4:25 PM ET
  • Venue: Lambeau Field, Green Bay, WI
  • TV: FOX

Los Angeles Rams (5-3) At Pittsburgh Steelers (4-4)

Rams vs. Steelers
-190 Moneyline +165
-3.5 (-110) Spread +3.5 (-110)
O 44.5 (-110) Total U 44.5 (-110)
Bet On Rams vs. Steelers NFL Week 10 Game At

The Rams are back in contention after two wins in a row. Facing Atlanta and Cincinnati on consecutive weeks sure helped the Rams be back in the playoffs talk. Los Angeles enter this game after spending last weekend on a bye.

Pittsburgh has won three straight against the Chargers, Dolphins, and Colts. It hasn’t been pretty, but the team is now at .500 with a chance for a wildcard spot.

The Steelers defense has the second most takeaways this season with 22, only behind the Patriots who are on a historic pace in that department.

The Rams opened -3.5 on the road, and the betting line has danced around -3.5 and -4 over the last few days. You must be able to find the number that you like the most by shopping around on several different sports betting sites.

Rams Vs. Steelers Game Information

  • Date: Sunday, November 10, 2019
  • Game Time: 4:25 PM ET
  • Venue: Heinz Field, Pittsburgh, PA
  • TV: FOX

Minnesota Vikings (6-3) At Dallas Cowboys (5-2)

Vikings vs. Cowboys
 N/A Moneyline  N/A
+3 (-110) Spread -3 (-110)
 N/A Total  N/A
Bet On Vikings vs. Cowboys NFL Week 10 Game At

The Vikings wasted a great chance to tie the Packers at the top of the NFC North division. Minnesota is missing WR Adam Thielen, who is QB Kirk Cousins’ security blanket.

Thielen played one quarter against Kansas City and reinjured his hamstring. He’s questionable for Sunday. Dallas will be on a short week after beating the Giants on Monday Night.

Dallas has won two straight against divisional opponents and is back to control the NFC East destiny. What’s coming next will tell a lot about the Cowboys. Dallas will face the Vikings, Lions, and Patriots in the next three weeks.

Vikings vs. Cowboys Game Information

  • Date: Sunday, November 10, 2019
  • Game Time: 8:20 PM ET
  • Venue: AT&T Stadium, Arlington, TX
  • TV: NBC

Seattle Seahawks (7-2) At San Francisco 49ers (8-0)

Seahawks vs. 49ers
+230 Moneyline -270
+6 (-110) Spread -6 (-110)
O 46 (-110) Total U 46 (-110)
Bet On Seahawks vs. 49ers NFL Week 10 Game At

It’s almost a miracle to see the best game of the week on Monday Night Football. The ESPN executives are probably excited they finally got a break from a wicked lineup of games.

Seattle’s defense is suspect listed as they are fifth-worst against the pass this season. They will face QB Jimmy Garoppolo, who is coming off a 4 TD performance against Arizona.

San Francisco has the advantage of having 11 days to prepare for this divisional matchup. The 49ers have the best total defense in the NFL and will go against the MVP front runner Russell Wilson.

Russ has thrown 22 touchdowns and just one interception this season. Last weekend he torched the Buccaneers lousy defense with five touchdown passes.

The 49ers opened -7 for this game, but now the line has dropped to -6 in most markets. There are a few sports betting sites with the line at -6.5, but the touchdown difference is gone at most sportsbooks.

Seahawks Vs. 49ers Game Information

  • Date: Monday, November 11, 2019
  • Game Time: 8:15 PM ET
  • Venue: Levi’s Stadium, Santa Clara, CA
  • TV: ESPN

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Alonzo Solano

Alonzo Solano - Sports Analyst & Picks Writer

Alonzo is a Sports Analyst who has covered College Football and NFL odds for SafestBettingSites but don’t be surprised if you read him on any other sport. He’s a gaming analyst looking for winners every weekend.

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