NFL Week 12 Expert Betting Preview | Top Matchups Odds & Tips

NFL Week 12 Preview Odds & Picks

In Week 12, there will be three Thanksgiving matchups, seven 1 PM games on Sunday, and three more in the late window, including the marquee clash between Pat Mahomes and Tom Brady for the fourth time.

This is what you need to know about the best matchups in NFL Week 12.

NFL Week 12 Games Betting Odds

Baltimore Ravens (6-4) at Pittsburgh Steelers (10-0)

Baltimore Ravens Vs. Pittsburgh Steelers
+188 Moneyline -225
+4.5 (-116) Spread -4.5 (-104)
O 45 (-110) Total U 45 (-110)
Bet On Baltimore Ravens Vs. Pittsburgh Steelers NFL Week 12 Game at BetNow

Baltimore Ravens Vs. Pittsburgh Steelers Game Info:

  • Date: Thursday, November 26, 2020 | 8:20 PM ET
  • Venue: Heinz Field, Pittsburgh, PA
  • TV: NBC

Baltimore Ravens Vs. Pittsburgh Steelers Breakdown

Thanksgiving night will feature an AFC North rematch between the Ravens and Steelers. Baltimore is coming off their second loss in a row after losing 30-24 to the Tennessee Titans in overtime. It’s the Ravens’ third defeat in the last four outings.

Baltimore won’t have RB JK Dobbins and Mark Ingram on Thursday Night. The Ravens placed both on the COVID-19 Reserve list.

The Steelers do not understand what it is like to lose in 2020. Pittsburgh is 10-0 for the first time in franchise history after taking care of the Jacksonville Jaguars 27-3 last weekend.

Pittsburgh listed WR Juju Smith-Shuster as questionable face the Ravens due to a toe injury.

The Steelers opened -3.5 at home but the line moved to -4.5.

Tennessee Titans (7-3) at Indianapolis Colts (7-3)

Tennessee Titans Vs. Indianapolis Colts
+170 Moneyline -200
+4 (-116) Spread -4 (-104)
O 51 (-110) Total U 51 (-110)
Bet On Tennessee Titans Vs. Indianapolis Colts NFL Week 12 Game at BetNow

Tennessee Titans Vs. Indianapolis Colts Game Info:

  • Date: Sunday, November 28, 2020 | 1:00 PM ET
  • Venue: Lucas Oil Stadium, Indianapolis, IN
  • TV: CBS

Tennessee Titans Vs. Indianapolis Colts Breakdown

The AFC South will be at stake when the Titans and Colts meet for the second time in three weeks. Tennessee beat the Ravens in overtime while Indianapolis took care of the Green Bay Packers 34-31 in OT.

The Titans lost LB Jayon Brown for the season with a dislocated and fractured elbow. Safety Kenny Vaccaro didn’t play against the Ravens because of a concussion. His status for Sunday is uncertain.

Colts’ QB Philip Rivers is dealing with a sore toe. Coach Frank Reich said he expects Rivers to play against the Titans.

Indianapolis opened -4, and the line hasn’t moved since.

Kansas City Chiefs (9-1) at Tampa Bay Buccaneers (7-4)

Kansas City Chiefs Vs. Tampa Bay Buccaneers
N/A Moneyline N/A
-3 (-116) Spread +3 (-104)
N/A Total N/A
Bet On Kansas City Chiefs Vs. Tampa Bay Buccaneers NFL Week 12 Game at BetNow

Kansas City Chiefs Vs. Tampa Bay Buccaneers Game Info:

  • Date: Sunday, November 28, 2020 | 4:25 PM ET
  • Venue: Raymond James Stadium, Tampa, FL
  • TV: CBS

Kansas City Chiefs Vs. Tampa Bay Buccaneers Breakdown

The Chiefs battled to beat the Raiders 35-31 on Sunday night, but everything is easy when you have Patrick Mahomes. Kansas City has won five in a row since their only loss in the season to Las Vegas in Week 5.

Kansas City expects Sammy Watkins (hamstring/calf) to be available against the Buccaneers in Week 12.

The Buccaneers had another atrocious performance in Primetime, losing 27-24 to the LA Rams. It was their second loss in the last three games. There were no injuries reported on Tampa Bay after Monday Night.

The Chiefs opened -3.5 on the road, but the line is now at -3.

Chicago Bears (5-5) at Green Bay Packers (7-3)

Chicago Bears Vs. Green Bay Packers
N/A Moneyline N/A
+9 (-116) Spread -4 (-104)
N/A Total N/A
Bet On Chicago Bears Vs. Green Bay Packers NFL Week 12 Game at BetNow

Chicago Bears Vs. Green Bay Packers Game Info:

  • Date: Sunday, November 28, 2020 | 8:20 PM ET
  • Venue: Lambeau Field, Green Bay, WI
  • TV: NBC

Chicago Bears Vs. Green Bay Packers Breakdown

The Bears didn’t play in Week 11, and coach Matt Nagy hasn’t named a starter for Week 12. Nick Foles is dealing with a hip injury, and Mitch Trubisky hasn’t dressed in the last two games due to a shoulder problem.

The Green Bay Packers lost to the Indianapolis Colts in overtime last week after turning the ball four times. Green Bay remains at the top of the NFC North, despite the loss. Center Corey Linsley is dealing with a back injury. He’s questionable to face Chicago.

This game’s line opened with the Packers -9 but is off the board in most places because of the QB news in Chicago.

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Alonzo Solano

Alonzo Solano - Sports Analyst & Picks Writer

Alonzo is a Sports Analyst who has covered College Football and NFL odds for SafestBettingSites but don’t be surprised if you read him on any other sport. He’s a gaming analyst looking for winners every weekend and a casino enthusiast.

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