NFL Draft Betting Predictions 2021 | Best Bets & Odds

NFL Draft predictions and betting odds

There is nothing like some early NFL Draft predictions. Well, it’s actually not that early with the Draft coming in a few weeks, but we are right on time to find some value around some of these bets.

The 2021 NFL draft will look a lot more like a standard NFL Draft compared to last year’s nearly entirely virtual event. It will have fans, and plenty of players will be on-site in Cleveland.

The first round starts on Thursday, April 29, and the rest will go on all weekend.

This NFL Draft preview won’t hit any mock draft, but will have some of the best bets available at the top NFL sportsbooks we recommend.

Best 2021 NFL Draft Bets – Betting Odds & Predictions

Who Will Be The 3rd Pick Overall In The Draft?

Player Odds At
Sportsbetting logo
Mac Jones -190
Justin Fields +120
Trey Lance +500
Zach Wilson +2500

We know Trevor Lawrence will go to Jacksonville with the first overall pick.

It’s pretty much a given that Zach Wilson will go to the NY Jets with the second. Although if there is a team who can mess this up, it is the Jets.

The 49ers traded three first-round picks for the chance to select their third-best prospect in this year’s draft.

That’s a lot of picks, if you ask me, but that’s a discussion for another day.

Either way, the San Francisco 49ers watched Mac Jones’ pro day before going to Justin Fields’. Jones didn’t blow anybody away, as you can see in the video below.


Justin Fields organized a second pro day so 49ers HC Kyle Shanahan can see him live. In the first one, Field dropped bombs like this one: 


San Francisco needs to think about this pick carefully. They traded away much of their future to select their next QB. 

The Niners choosing Mac Jones is not a certainty, which means the value is all on Fields.

If you can grab him at +120, you will be getting a lot of value on a QB that might change the 49ers’ mind just with a live throwing exercise.

  • Bet: Justin Fields +120

Trey Lance Selected At What Number?

Trey Lance Selected At What Number?
Over 6½ Selection Number -120 Sportsbetting Sportsbook
Under 6½ Selection Number -120

With all the talk going between Justin Fields, Mac Jones, Trevor Lawrence, and Zach Wilson, Trey Lance seems the forgotten name of the top 5 QBs in the 2021 draft.

Two things are going against Lance. First, he played for North Dakota State.

This wasn’t an excuse for the Philadelphia Eagles when they selected QB Carson Wentz in 2016, but the Bison still are in a subdivision level.

The second, and perhaps the most important, is he didn’t play in 2020.

It’s not his fault the season got canceled due to the COVID-19 pandemic, but it leaves too many questions to answer. Meaning there isn’t enough tape for scouts to evaluate his potential.

With the Jaguars, Jets, and Niners selecting other QBs, not name Lance, the following three teams are franchises without a QB need.

Cincinnati and Miami have their QBs of the future, while Atlanta still thinks Matt Ryan has something in the tank.

Even if Atlanta selects a QB with the 4th overall pick thinking about the next ten years, Trey Lance seems off their radar.

Unless someone goes crazy and trade-up, Lance should still be on the board past the 6th pick.

  • Bet: Trey Lance Over 6½ Selection Number -120

Ja’Maar Chase Selected At What Number?

Ja’Maar Chase Selected At What Number?
Under 6.5 Selection Number -190 Sportsbetting Sportsbook
Over 6.5 Selection Number +145

Sometimes there is no reason to chase value. Just bet a winner when you see it, without looking at the price.

Where Ja’Maar Chase will get selected is one of those situations. He will be the first wideout picked, and teams like Atlanta, Cincinnati, or Miami won’t pass on him.


The Dolphins, in particular, have both an interest and need for a player of his caliber.

Just grab Chase to go in the first six picks on the draft.

  • Bet: Ja’Maar Chase Under 6.5 Selection Number -190 

More NFL Draft Betting Tips

The online sportsbooks have plenty of NFL draft betting odds to choose from. I’m just giving you a few tips on the ones I like the most.

Go nuts and bet any of the following:

First Pick Of The 2021 NFL Draft

Player Odds At
Sportsbetting logo
Trevor Lawrence -10000
Zach Wilson +1200
Justin Fields +2000
Penei Sewell +3300

2nd Draft Pick Overall

Player Odds At
Sportsbetting logo
Zach Wilson -2500
Justin Fields +850
Trey Lance +1600
Penei Sewell +3300

1st Defensive Player Picked In The Draft

Player Odds At
Sportsbetting logo
Patrick Surtain II -120
Micah Parsons +200
Jaycee Horn +350
Kwity Paye +550
Jaelan Phillips +1200

First OL To Be Picked In The 2021 NFL Draft

Player Odds At
Sportsbetting logo
Penei Sewell -400
Rashawn Slater +250

First RB To Be Picked In The Draft

Player Odds At
Sportsbetting logo
Najee Harris -175
Travis Etienne +180
Javonte Williams +500

First WR To Be Picked In The NFL Draft

Player Odds At
Sportsbetting logo
Ja’Marr Chase -700
DeVonta Smith +600
Jaylen Waddle +650

DeVonta Smith Selected At What Number?

DeVonta Smith Selected At What Number?
Under 11½ Selection Number -130 Sportsbetting Sportsbook
Over 11½ Selection Number -110

Jaylen Waddle Selected At What Number?

Jaylen Waddle Selected At What Number?
Under 11½ Selection Number -135 Sportsbetting Sportsbook
Over 11½ Selection Number -105

Kyle Pitts Selected At What Number?

Kyle Pitts Selected At What Number?
Over 5½ Selection Number -150 Sportsbetting Sportsbook
Under 5½ Selection Number +110

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Alonzo Solano

Alonzo Solano - Sports Analyst & Picks Writer

Alonzo is a Sports Analyst who has covered College Football and NFL odds for SafestBettingSites but don’t be surprised if you read him on any other sport. He’s a gaming analyst looking for winners every weekend.

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